Host-microbe Interactions in Chemotherapy-induced Oral Mucositis
نویسندگان
چکیده
Introduction & Objectives More and more evidence is emerging that microbiota are involved in the development and severity of oral mucositis, an inflammation and ulceration of the mucosa after chemotherapy. It is known that the microbiome is changed during mucositis and that chemotherapy is often complicated with local and even systemic infections. But still little is known about the role of oral commensals in the onset, development, and duration of oral mucositis. In this study, we want to explore the role of host-microbe interactions in chemotherapy-induced oral mucositis by means of an in-house developed in vitro model.
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